Vitamin E: Mechanisms of Action as Tumor Cell Growth Inhibitors
نویسندگان
چکیده
منابع مشابه
Adriamycin-activated macrophages as tumor growth inhibitors.
Flow cytometry has been used to study the influence of Adriamycin- and Corynebacterium parvum-elicited cytostatic macrophages on the cell cycle of HeLa cells. Macrophages harvested from the peritoneal cavity of mice given i.p. injections of Adriamycin retain cytostatic activity for 3 to 4 days in vivo. Many of these macrophages fluoresced with the red emission spectra characteristic of Adriamyc...
متن کاملCell Death Inducing Microbial Protein Phosphatase Inhibitors—Mechanisms of Action
Okadaic acid (OA) and microcystin (MC) as well as several other microbial toxins like nodularin and calyculinA are known as tumor promoters as well as inducers of apoptotic cell death. Their intracellular targets are the major serine/threonine protein phosphatases. This review summarizes mechanisms believed to be responsible for the death induction and tumor promotion with focus on the interdep...
متن کاملTumor cell surface heparan sulfate as cryptic promoters or inhibitors of tumor growth and metastasis.
Heparan sulfate glycosaminoglycans, present at the cell surface and in the extracellular matrix that surrounds cells, are important mediators of complex biological processes. Furthermore, it is now apparent that cells dynamically regulate the structure of their heparan sulfate "coat" to differentially regulate extracellular signals. In the present study, the importance of sequence information c...
متن کاملInhibition of Gastric Tumor Cell Growth Using Seed-targeting LNA as Specific, Long-lasting MicroRNA Inhibitors
MicroRNAs regulate eukaryotic gene expression upon pairing onto target mRNAs. This targeting is influenced by the complementarity between the microRNA "seed" sequence at its 5' end and the seed-matching sequences in the mRNA. Here, we assess the efficiency and specificity of 8-mer locked nucleic acid (LNA)-modified oligonucleotides raised against the seeds of miR-372 and miR-373, two embryonic ...
متن کاملVitamin C and Tumor Growth*
The association of vitamin C with tissue growth and physiologic activity raises the question of its relative importance in the growth and maintenance of neoplastic cells. A review of the previously reported observations on this subject has been made by Minor and Ramirez in connection with their studies in the utilization of vitamin C by cancer patients. They found that in 7 normal persons, in 1...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: The Journal of Nutrition
سال: 2001
ISSN: 0022-3166,1541-6100
DOI: 10.1093/jn/131.1.161s